diff --git a/wolframclient/serializers/encoders/pandas.py b/wolframclient/serializers/encoders/pandas.py
index a3874334..f33d0af9 100644
--- a/wolframclient/serializers/encoders/pandas.py
+++ b/wolframclient/serializers/encoders/pandas.py
@@ -183,3 +183,8 @@ def encoder_panda_dataframe(serializer, o):
                 ", ".join(PANDAS_PROPERTIES["pandas_dataframe_head"]), head
             )
         )
+
+
+@encoder.dispatch(pandas.NaT)
+def encode_pandas_not_a_time(serializer, o):
+    return serializer.serialize_symbol(b"Indeterminate")
diff --git a/wolframclient/utils/api.py b/wolframclient/utils/api.py
index 19855896..8513f641 100644
--- a/wolframclient/utils/api.py
+++ b/wolframclient/utils/api.py
@@ -168,6 +168,7 @@
     SparseSeries="pandas.SparseSeries",
     SparseArray="pandas.SparseArray",
     bdate_range="pandas.bdate_range",
+    NaT="pandas.api.typing.NaTType",
 )
 
 aiohttp = API(