diff --git a/Lib/_pyrepl/historical_reader.py b/Lib/_pyrepl/historical_reader.py
index c4b95fa2e81ee6..7a17c31f126abe 100644
--- a/Lib/_pyrepl/historical_reader.py
+++ b/Lib/_pyrepl/historical_reader.py
@@ -31,7 +31,7 @@
 
 
 isearch_keymap: tuple[tuple[KeySpec, CommandName], ...] = tuple(
-    [("\\%03o" % c, "isearch-end") for c in range(256) if chr(c) != "\\"]
+    [("\\%03o" % c, "isearch-end") for c in range(256) if chr(c) not in ("\\", "\x1b")]
     + [(c, "isearch-add-character") for c in map(chr, range(32, 127)) if c != "\\"]
     + [
         ("\\%03o" % c, "isearch-add-character")
@@ -45,6 +45,7 @@
         (r"\C-c", "isearch-cancel"),
         (r"\C-g", "isearch-cancel"),
         (r"\<backspace>", "isearch-backspace"),
+        (r"\x1b[200~", "isearch-bracketed-paste"),
     ]
 )
 
@@ -209,6 +210,21 @@ def do(self) -> None:
         r.pop_input_trans()
         r.dirty = True
 
+class isearch_bracketed_paste(commands.Command):
+    def do(self) -> None:
+        r = self.reader
+        b = r.buffer
+        done = "\x1b[201~"
+        data = ""
+        while done not in data:
+            ev = r.console.getpending()
+            data += ev.data
+        paste_content = data.replace(done, "")
+        r.isearch_term += paste_content
+        r.dirty = True
+        if "".join(b[r.pos:r.pos+len(r.isearch_term)]) != r.isearch_term:
+            r.isearch_next()
+
 
 @dataclass
 class HistoricalReader(Reader):
@@ -245,6 +261,7 @@ def __post_init__(self) -> None:
             isearch_backspace,
             isearch_forwards,
             isearch_backwards,
+            isearch_bracketed_paste,
             operate_and_get_next,
             history_search_backward,
             history_search_forward,
diff --git a/Lib/test/test_pyrepl/test_pyrepl.py b/Lib/test/test_pyrepl/test_pyrepl.py
index 35a1733787e7a2..6839147b944a3f 100644
--- a/Lib/test/test_pyrepl/test_pyrepl.py
+++ b/Lib/test/test_pyrepl/test_pyrepl.py
@@ -1509,6 +1509,44 @@ def test_bracketed_paste_single_line(self):
         output = multiline_input(reader)
         self.assertEqual(output, input_code)
 
+    def test_bracketed_paste_in_isearch(self):
+        paste_start = "\x1b[200~"
+        paste_end = "\x1b[201~"
+
+        events = itertools.chain(
+            # Add some history
+            code_to_events("print('hello')\n"),
+            # Search for 'hello'
+            [
+                Event(evt="key", data="\x12", raw=bytearray(b"\x12")),
+            ],
+            code_to_events(paste_start),
+            code_to_events("hello"),
+            code_to_events(paste_end),
+            [
+                Event(evt="key", data="\n", raw=bytearray(b"\n")),
+                Event(evt="key", data="\n", raw=bytearray(b"\n")),
+            ],
+            [
+                Event(evt="key", data="\x12", raw=bytearray(b"\x12")),
+            ],
+            # Search for 'world', which should not be found
+            code_to_events(paste_start),
+            code_to_events("world"),
+            code_to_events(paste_end),
+            [
+                Event(evt="key", data="\n", raw=bytearray(b"\n")),
+                Event(evt="key", data="\n", raw=bytearray(b"\n")),
+            ],
+        )
+
+        reader = self.prepare_reader(events)
+        multiline_input(reader)
+        output = multiline_input(reader)
+        self.assertEqual(output, "print('hello')")
+        output = multiline_input(reader)
+        self.assertEqual(output, "")
+
 
 @skipUnless(pty, "requires pty")
 class TestDumbTerminal(ReplTestCase):
diff --git a/Misc/NEWS.d/next/Library/2026-03-02-02-51-27.gh-issue-145375.j9r8TS.rst b/Misc/NEWS.d/next/Library/2026-03-02-02-51-27.gh-issue-145375.j9r8TS.rst
new file mode 100644
index 00000000000000..4f9eda901db34f
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2026-03-02-02-51-27.gh-issue-145375.j9r8TS.rst
@@ -0,0 +1 @@
+Handle bracketed paste in :mod:`!_pyrepl` isearch mode.